Very different workouts for the reasons that you listed.
Writing about strides makes me think that you’re a runner? If that’s the case our gym-based ME for runners would be a better program than our weighted carries for mountaineers.
What is the training difference between doing weighted muscular endurance (backpack with heavy weight on steep vert) workouts vs hill strides in terms of the benefits to the body? Maybe the weighted ME will help with muscle fibers holding up longer and hill strides will increase muscular efficiency? Thoughts?