So from what I have learned through conversations is that there is some small amount of studies that may indicate that chronic use of ibuprofen (ingredient of Advil) may interfere with protein synthesis and subsequently can interfere with long term performance gains. I am unsure how much ibuprofen the participants were taking and I am unsure if the same holds for acetaminophen (generic name for Tylenol).
Everyone needs to figure out what works for them but I for one avoid taking any anti inflammatories. I already am not good at listening to my body and blunting the soreness or pain is a surefire way for me to overtrain and get hurt. I have supplemented soreness with ice cold showers, mobility, and foam rolling.
Idiotic as it sounds I never drank protein shakes at all until this year and that makes a big difference when done within an hour of finishing a major ME or MAX session. I know that’s common knowledge but I’m slow to the party I guess.